Dapoxetine premature ejaculation

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    Dapoxetine premature ejaculation


    The European Association of Urology 2014 guidelines on male sexual dysfunction state that although premature ejaculation is a very common male sexual dysfunction (with prevalence rates of 20% to 30%), its aetiology is poorly understood. In the Diagnostic and Statistical Manual of Mental Disorders IV-Text Revision (DSM-IV-TR), premature ejaculation is defined as 'persistent or recurrent ejaculation with minimal sexual stimulation before, on, or shortly after penetration and before the person wishes it. The clinician must take into account factors that affect duration of the excitement phase, such as age, novelty of the sexual partner or situation, and recent frequency of sexual activity'. The major point of debate between the DSM-IV-TR definition of premature ejaculation and other definitions is quantifying the time to ejaculation, which is usually described as the intravaginal ejaculatory latency time (IELT). Premature ejaculation is classified as 'lifelong' (primary) or 'acquired' (secondary). Lifelong premature ejaculation is characterised by onset from the first sexual experience and remaining during life with ejaculation occurring too fast (before vaginal penetration or less than 1 to 2 minutes after). Acquired premature ejaculation is characterised by a gradual or sudden onset - after previous normal ejaculation experiences; time to ejaculation is short but usually not as short as in lifelong premature ejaculation. Priligy is a treatment designed specifically for men who have problems with premature ejaculation. You take a tablet a couple of hours before you intend to have sex, and this can help you last longer before you climax. Back to top Priligy tablets will only be prescribed after careful assessment by a doctor to make sure they are appropriate for you. It's a prescription-only medicine, but it's possible to buy Priligy from online pharmacies after filling in a medical questionnaire that's checked by a doctor. Back to top Back to top Priligy tablets contain the active ingredient dapoxetine, which is a type of medicine known as a short-acting selective serotonin re-uptake inhibitor. Dapoxetine works by increasing the activity of serotonin in the nervous system. Serotonin is a neurotransmitter that is involved in passing messages between nerve cells. It has various functions in the body and is involved in sending the nerve messages that result in ejaculation. Increasing the activity of serotonin in the nervous system helps to increase the time it takes to ejaculate and improve control over the ejaculation.

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    Summary of the evidence on dapoxetine for premature ejaculation to inform local NHS planning and decision-making. Dapoxetine, a short-acting SSRI, is the first drug to be marketed for premature ejaculation. After oral administration, peak plasma concentrations of dapoxetine are reached after an hour. Elimination is relatively rapid and the terminal half-life is approximately 19 hours. Dapoxetine is the most effective and safest medication for the treatment of premature ejaculation. In 2012, Dr. Chris McMahon conducted a study in which more than 6,000 men participated. Dapoxetine is sold under the brand name Priligy in the USA.

    Some of the views expressed in the following notes on newly approved products should be regarded as preliminary, as there may have been limited published data at the time of publication, and little experience in Australia of their safety or efficacy. However, the Editorial Executive Committee believes that comments made in good faith at an early stage may still be of value. Before new drugs are prescribed, the Committee believes it is important that more detailed information is obtained from the manufacturer's approved product information, a drug information centre or some other appropriate source. Approved indication: premature ejaculation Priligy (A Menarini) 30 mg tablets Australian Medicines Handbook section 13.3.2 Delayed ejaculation is an adverse effect of selective serotonin reuptake inhibitors (SSRIs) in men. Dapoxetine, a short-acting SSRI, is the first drug to be marketed for premature ejaculation. After oral administration, peak plasma concentrations of dapoxetine are reached after an hour. Elimination is relatively rapid and the terminal half-life is approximately 19 hours. Dapoxetine, which is generally categorized as a fast-acting SSRI, was developed specifically to treat this condition. It may be effective at the first dose (ie, on demand) when given 1-3 hours before sexual intercourse, and its adverse-effect profile is comparable to those of other SSRIs. Dapoxetine has been approved in a number of countries but not yet in the United States. In a study of men with both premature ejaculation and erectile dysfunction who were on phosphodiesterase type 5 (PDE5) therapy, dapoxetine provided treatment benefit and was generally well tolerated. Samuel G Deem, DO Faculty, Department of Urology, Charleston Area Medical Center Samuel G Deem, DO is a member of the following medical societies: American College of Surgeons, American Osteopathic Association, American Urological Association, Endourological Society, Society of Urologic Oncology, American Society of Clinical Oncology, American College of Osteopathic Surgeons Disclosure: Nothing to disclose. Kevin P Brown, DO Resident Physician, Department of Urology, Charleston Area Medical Center Kevin P Brown, DO is a member of the following medical societies: American Osteopathic Association, American Urological Association Disclosure: Nothing to disclose. Edward David Kim, MD, FACS Professor of Surgery, Division of Urology, University of Tennessee Graduate School of Medicine; Consulting Staff, University of Tennessee Medical Center Edward David Kim, MD, FACS is a member of the following medical societies: American College of Surgeons, American Society for Reproductive Medicine, American Society of Andrology, American Urological Association, Sexual Medicine Society of North America, Tennessee Medical Association Disclosure: Serve(d) as a speaker or a member of a speakers bureau for: Endo.

    Dapoxetine premature ejaculation

    Dapoxetine and the treatment of premature ejaculation, Dapoxetine for premature ejaculation Australian Prescriber

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  6. Dapoxetine aka priligy is a prescribed SSRI that is used to treat PE. And for some men, taking priligy for PE can be effective. Fortunately, there is a lot of research-based results available for men to review before deciding to try dapoxetine to treat their premature ejaculation.

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    Ejaculation problems Ejaculation problems are common sexual problems in men. The three main problems are premature ejaculation delayed ejaculation. An SSRI specifically designed to treat premature ejaculation, known as dapoxetine Priligy, has now been licensed in the UK. Local NHS authorities can choose to prescribe it on the NHS. The dapoxetine phase II and III study enrolment criteria may result in. OverviewMedical usesContraindicationsAdverse effectsMechanism of actionsPharmacokinetics

     
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