Retin-a is medical drug that is used for clearing of problematical skin from acne. First announce was more than 30 years ago, given drug is included in number of the most effective remedies against acne, which not only clear skin from acne, but also transforming it and gives a fresh look. In Retina-A contain are included such components as Retin acid and tretinoinum. Production form of Retin-A differently occurs: in form of gel or cream, differs by level of concentration depending on for what skin it is purposed. Tretinoinum is main active substance in Retin-a contain which makes upper layer of skin more thin, by this way activating formation of new cells, production of collagen, building of other more fat layer of epidermis. In that way due to applying of this drug, skin can be quickly and effectively cleaned from acne, age spots, freckles and even scars without using beauty treatments. Such a simple way of treatment acne is not only active but also safe. 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Tretinoin (vitamin A acid) is a retinoid used in treatment of skin conditions such as severe acne (pustules), rosacea (red spots on the forehead, cheeks and nose), stretch marks, wrinkles and pigmentation. causes the damaged skin to be replaced by a new skin by accelerating cell division in the upper skin layer. This way impurities such as stains, wrinkles and obstructed sebaceous glands disappear, and subcutaneous inflammations can heal. Before you start using Tretinoin, please read patient leaflet if available or consult your pharmacist if you have any questions about Tretinoin before taking this medication. Apply Tretinoin Cream or lotion once a day in a thin layer on the acne affected areas of clean and dry skin (preferably in the evening before bed). Treat only necessary areas and avoid contact with eyes, nose, wounds and healthy skin. If this happens, rinse the cream or lotion thoroughly with water. 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